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Susceptibility to noise exposure during postnatal development in rats
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SYSNO ASEP 0173435 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Susceptibility to noise exposure during postnatal development in rats Author(s) Rybalko, Natalia (UEM-P) RID
Syka, Josef (UEM-P) RIDSource Title Hearing Research. - : Elsevier - ISSN 0378-5955
Roč. 155, - (2001), s. 32-40Number of pages 9 s. Language eng - English Country NL - Netherlands Keywords noise exposure ; enhancement Subject RIV FH - Neurology R&D Projects NK4747 GA MZd - Ministry of Health (MZ) GA309/97/0830 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z5039906 - UEM-P Annotation Noise exposure in young rats produced an adult-like pattern with an elevation of hearing thresholds. Recovery of hearing thresholds in the high frequency range depended on the age of the animal at the time of exposure. In all animals aged less that 6-7 weeks, exposure resulted in a permanent threshold shift in the range of 4-32 kHz. Similar to adult rats, young rats exposed to noise exhibited an enhancement of MLR aplitudes. In several rats exposed at 3-5 weeks of age, the recovery period to normal amplitudes was substantially prolonged and lasted 4-8 weeks in commparison with 1-2 weeks in adult rats. These results demonstrate a greater susceptibility to noise exposure in rats during the first 5 postnatal weeks. Workplace Institute of Experimental Medicine Contact Arzuv Čaryjeva, arzuv.caryjeva@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Year of Publishing 2002
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