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Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization
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SYSNO ASEP 0047641 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Ostatní články Title Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization Title Dimethylsulfoxid posiluje apoptózu zprostředkovanou receptory smrti v lidské leukemické linii U937 prostřednictvím posílení depolarizace mitochondriální membrány Author(s) Vondráček, Jan (BFU-R) RID, ORCID
Souček, Karel (BFU-R) RID, ORCID
Sheard, M. A. (US)
Chramostová, Kateřina (BFU-R)
Andrysík, Zdeněk (BFU-R)
Hofmanová, Jiřina (BFU-R) RID, ORCID
Kozubík, Alois (BFU-R) RID, ORCIDSource Title Leukemia Research. - : Elsevier - ISSN 0145-2126
Roč. 30, č. 1 (2006), s. 81-89Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords human myeloid leukemia ; DMSO ; apoptosis Subject RIV BO - Biophysics R&D Projects GA524/03/0766 GA ČR - Czech Science Foundation (CSF) CEZ AV0Z50040507 - BFU-R (2005-2011) Annotation In the present study we described the effects of DMSO on susceptibility of human myeloid leukemia U937 cells towards ligation of distinct death receptors (DRs) were investigated. DMSO sensitized cells towards induction of apoptosis by anti-Fas antibody, tumour necrosis factor-alpha or TNF-related apoptosis-inducing ligand (TRAIL). Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2007
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