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An enigmatic catalase of Blastocrithidia
- 1.0520657 - BC 2020 RIV NL eng J - Journal Article
Bianchi, C. - Kostygov, A.Y. - Kraeva, N. - Záhonová, Kristýna - Horáková, Eva - Sobotka, Roman - Lukeš, Julius - Yurchenko, Vyacheslav
An enigmatic catalase of Blastocrithidia.
Molecular and Biochemical Parasitology. Roč. 232, SEP 2019 (2019), č. článku 111199. ISSN 0166-6851. E-ISSN 1872-9428
R&D Projects: GA MŠMT(CZ) LL1601; GA MŠMT(CZ) EF16_019/0000759
Institutional support: RVO:60077344 ; RVO:61388971
Keywords : evolution * Oxygen peroxide * Catalase * Trypanosomatidae
OECD category: Genetics and heredity (medical genetics to be 3); Biochemistry and molecular biology (MBU-M)
Impact factor: 1.571, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0166685119300684
Here we report that trypanosomatid flagellates of the genus Blastocrithidia possess catalase. This enzyme is not phylogenetically related to the previously characterized catalases in other monoxenous trypanosomatids, suggesting that their genes have been acquired independently. Surprisingly, Blastocrithidia catalase is less enzymatically active, compared to its counterpart from Leptomonas pyrrhocoris, posing an intriguing biological question why this gene has been retained in the evolution of trypanosomatids.
Permanent Link: http://hdl.handle.net/11104/0305298
Number of the records: 1