Voltammetric determination of cancer biomarker 5-hydroxyindole-3-acetic acid at screen-printed carbon electrodes

0466673 - ÚFCH JH 2017 RIV CZ eng C - Conference Paper (international conference)
Makrlíková, Anna - Navrátil, Tomáš - Barek, J. - Vyskočil, V.
Voltammetric determination of cancer biomarker 5-hydroxyindole-3-acetic acid at screen-printed carbon electrodes.
Proceedings of the 12th ISC Modern Analytical Chemistry. Prague: Charles University of Prague, 2016 - (Nesměrák, K.), s. 140-143. ISBN 978-80-7444-044-1.
[ISC Modern Analytical Chemistry /12./. Prague (CZ), 22.09.2016-23.09.2016]
Institutional support: RVO:61388955
Keywords : differential pulse voltammetry * tumor biomarker * screen-printed carbon electrodes
Subject RIV: CG - Electrochemistry

Tumor biomarker 5-hydroxyindole-3-acetic acid (5-HIAA) is a breakdown product of serotonin; level of this neurotransmitter can predict carcinoid tumors. 5-HIAA has been determined at screen-printed carbpon electrodes in the iptimum medium found: Britton-Robinson buffer (0.04 mol l-1, pH=3.0). Dependence of the peak current on the concentration of 5-HIAA was linear in the concentration region from 0.1 to 100 micromol l-1, with the limit of qiantification of 0.2 micromol l-1.
Permanent Link: http://hdl.handle.net/11104/0264923