0597925 - MBÚ 2025 RIV US eng J - Journal Article
Krynická, Vendula - Komenda, Josef
The Role of FtsH Complexes in the Response to Abiotic Stress in Cyanobacteria.
Plant and Cell Physiology. Roč. 65, č. 7 (2024), s. 1103-1114. ISSN 0032-0781. E-ISSN 1471-9053
R&D Projects: GA ČR(CZ) GA24-10227S; GA MŠMT(CZ) EH22_008/0004624
EU Projects: European Commission(CZ) 854126 - PhotoRedesign
Institutional support: RVO:61388971
Keywords : sp pcc 6803 * synechocystis-sp pcc-6803 * protein p-ii * photosystem-ii * quality-control * high-light * experimental validation * thylakoid membrane * gene-expression * repair * Cyanobacteria * FtsH * Nutrient stress * Photodamage * Photosystem
OECD category: Microbiology
Impact factor: 3.9, year: 2023
Method of publishing: Open access
Result website:
https://academic.oup.com/pcp/article/65/7/1103/7645829?login=trueDOI: https://doi.org/10.1093/pcp/pcae042

FtsH proteases (FtsHs) belong to intramembrane ATP-dependent metalloproteases which are widely distributed in eubacteria, mitochondria and chloroplasts. The best-studied roles of FtsH in Escherichia coli include quality control of membrane proteins, regulation of response to heat shock, superoxide stress and viral infection, and control of lipopolysaccharide biosynthesis. While heterotrophic bacteria mostly contain a single indispensable FtsH complex, photosynthetic cyanobacteria usually contain three FtsH complexes: two heterocomplexes and one homocomplex. The essential cytoplasmic FtsH1/3 most probably fulfills a role similar to other bacterial FtsHs, whereas the thylakoid FtsH2/3 heterocomplex and FtsH4 homocomplex appear to maintain the photosynthetic apparatus of cyanobacteria and optimize its functionality. Moreover, recent studies suggest the involvement of all FtsH proteases in a complex response to nutrient stresses. In this review, we aim to comprehensively evaluate the functions of the cyanobacterial FtsHs specifically under stress conditions with emphasis on nutrient deficiency and high irradiance. We also point to various unresolved issues concerning FtsH functions, which deserve further attention.
Permanent Link: https://hdl.handle.net/11104/0355707