Chiral membrane prepared by electrostatic modification of ionexchange membrane

0558497 - ÚCHP 2023 CZ eng K - Conference Paper (Czech conference)
Čížek, Jan
Chiral membrane prepared by electrostatic modification of ionexchange membrane.
Proceedings of Abstracts. Prague: Institute of Chemical Process Fundamentals of the CAS, 2022 - (Bendová, M.; Wagner, Z.), s. 7. ISBN 978-80-86186-24-5.
[Bažant Postgraduate Conference 2022. Prague (CZ), 13.06.2022-14.06.2022]
Institutional support: RVO:67985858
Keywords : chiral membrane * diffusion cells * electrostatic interaction
OECD category: Chemical process engineering

In this work, a simple and effective method for chiral membrane preparation is demonstrated, involving electrostatic interaction between negatively charged sulfobutylether-β-cyclodextrin (SBE-β-CD) as a chiral selector and a commercially available anionexchange membrane.The modified home-made chiral membrane was tested in diffusion cells to characterize its enantioselectivity towards D,L–Tryptophan. We demonstrated in our work that L–Tryptophan is preferentially absorbed into the membrane, while D–Tryptophan
is transported through the membrane with enantiomeric excess exceeding 80%. To increase the permeation rate of the membrane, thinner ion-exchange membrane substrate with higher degree of swelling is proposed.

Permanent Link: http://hdl.handle.net/11104/0332136