Ultra-fast oscillation detection in EEG signal from deep-brain microelectrodes

0556707 - ÚPT 2022 RIV US eng C - Conference Paper (international conference)
Trávníček, Vojtěch - Jurák, Pavel - Cimbálník, J. - Klimeš, Petr - Daniel, P. - Brázdil, M. … Total 7 authors
Ultra-fast oscillation detection in EEG signal from deep-brain microelectrodes.
IEEE Engineering in Medicine and Biology Society Conference Proceedings. In: 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). New York: IEEE, 2021, (2021), s. 265-268. ISBN 978-1-7281-1179-7.
[Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) /43./. online (MX), 01.11.2021-05.11.2021]
R&D Projects: GA MŠMT(CZ) LTAUSA18056
Institutional support: RVO:68081731
Keywords : high-frequency oscillations
OECD category: Medical engineering
https://ieeexplore.ieee.org/document/9629481

For the last decades, ripples 80-200Hz (R)and fast ripples 200-500Hz (FR) were intensively studied as biomarkers of the epileptogenic zone (EZ). Recently, Very fast ripples 500-1000Hz (VFR) and ultra-fast ripples 1000-2000Hz (UFR) recorded using standard clinical macro electrodes have been shown to be more specific for EZ. High-sampled microelectrode recordings can bring new insights into this phenomenon of high frequency, multiunit activity. Unfortunately, visual detection of such events is extremely time consuming and unreliable. Here we present a detector of ultra-fast oscillations (UFO, >1kHz). In an example of two patients, we detected 951 UFOs which were more frequent in epileptic (8.6/min) vs. non-epileptic hippocampus (1.3/min). Our detection method can serve as a tool for exploring extremely high frequency events from microelectrode recordings.
Permanent Link: http://hdl.handle.net/11104/0330853