Acoustofluidic platforms for particle manipulation

0548053 - ÚIACH 2023 RIV DE eng J - Journal Article
Novotný, Jakub - Lenshof, A. - Laurell, T.
Acoustofluidic platforms for particle manipulation.
Electrophoresis. Roč. 43, 7-8 (2022), s. 804-818. ISSN 0173-0835. E-ISSN 1522-2683
R&D Projects: GA MŠMT EF16_026/0008446
Grant - others:AV ČR(CZ) MSM200312001
Program: Program na podporu mezinárodní spolupráce začínajících výzkumných pracovníků
Institutional support: RVO:68081715
Keywords : acoustics * acoustofluidics * microfluidics * cell manipulation
OECD category: Analytical chemistry
Impact factor: 2.9, year: 2022
Method of publishing: Limited access

There is an increasing interest in acoustics for microfluidic applications. This field, com-monly known as acoustofluidics involves the interaction of ultrasonic standing waves withfluids and dispersed microparticles. The combination of microfluidics and the so-calledacoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation where it is possible to move and spatially local-ize these particles based on the different acoustophysical properties. While it was initiallysuggested that the acoustic forces could be harmful to the cells and could impact cell vi-ability, proliferation, or function via phenotypic or even genotypic changes, further stud-ies disproved such claims. This review is summarizing some interesting applications ofacoustofluidics in the manipulations of biomaterials, such as cells or subcellular vesicles,in works published mainly within the last years.
Permanent Link: http://hdl.handle.net/11104/0324173