Number of the records: 1
Chitosan-glucan complex hollow fibers reinforced collagen wound dressing embedded with aloe vera. Part I: Preparation and characterization
- 1.0532392 - ÚFM 2021 RIV GB eng J - Journal Article
Abdel-Mohsen, A. M. - Abdel-Rahman, R. M. - Kuběna, Ivo - Kobera, Libor - Spotz, Z. - Zboncak, M. - Přikryl, R. - Brus, Jiří - Jančar, J.
Chitosan-glucan complex hollow fibers reinforced collagen wound dressing embedded with aloe vera. Part I: Preparation and characterization.
Carbohydrate Polymers. Roč. 230, FEB (2020), č. článku 115708. ISSN 0144-8617. E-ISSN 1879-1344
Institutional support: RVO:68081723 ; RVO:61389013
Keywords : Chitosan-glucan * Hollow fiber * Collagen * Aloe vera * Degradation * Release properties * Wound dressing
OECD category: Polymer science; Polymer science (UMCH-V)
Impact factor: 9.381, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0144861719313761?via%3Dihub
Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first time by the freeze-dried process. Extraction process, morphology, mechanical properties, pore size, porosity, swelling ability, and degradation behavior of composites scaffold were investigated. CSGC hollow fibers were extracted from mycelium of Schizophyllum commune CSGC hollow fiber exhibited inner diameter of (600 +/- 250 nm) and outer fiber diameter of (2.5 +/- 0.5 mu m). The results of swelling and hydrolytic degradation studies demonstrated that the physicochemical of CO/CSGC@AV was significantly enhanced by CSGC in a concentration-dependent manner. The mechanical property of the CO/CSGC@AV was improved after encapsulated AV into CSGC hollow fibers compared with native CO. The pore size and porosity of the CO/CSGC@AV were slightly decreased in the presence of AV. All these results suggested that the new dressing scaffold has a potential for clinical skin regeneration, particularly for infected chronic wounds and ulcers.
Permanent Link: http://hdl.handle.net/11104/0310894
Number of the records: 1