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Matrices of ferromagnetic microwires for the control of cellular dynamics and localized delivery of medicines

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    0521437 - FZÚ 2020 RIV RU eng J - Journal Article
    Beklemisheva, A.V. - Yudanov, N.A. - Gurevich, A.A. - Panina, L.V. - Zablotskyy, Vitaliy A. - Deyneka, Alexander
    Matrices of ferromagnetic microwires for the control of cellular dynamics and localized delivery of medicines.
    Physics of Metals and Metallography. Roč. 120, č. 6 (2019), s. 556-562. ISSN 0031-918X. E-ISSN 1555-6190
    R&D Projects: GA MŠk(CZ) EF16_019/0000760
    Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
    Institutional support: RVO:68378271
    Keywords : diamagnetic capture * paramagnetic capture * ferromagnetic microwires
    Subject RIV: BM - Solid Matter Physics ; Magnetism
    OBOR OECD: Condensed matter physics (including formerly solid state physics, supercond.)
    Impact factor: 1.064, year: 2019
    https://doi.org/10.1134/s0031918x19060036

    A microwire in a biocompatible shell can be introduced into soft tissues or into blood vessels to maintain the biofunctioning of magnetic nanoparticles or stem cells with magnetic markers circulating in the blood. The magnetic fields created by the lattices of microwires are characterized by strong spatial gradients and can change over time in a specified manner. Such fields are necessary for the development of various magnetophoretic analytical chips for controlling the kinetics of cells and also for controlled drug delivery. A system of diametrically magnetized microwires is suggested in this paper, which possesses an energy minimum necessary for the stable capture of diamagnetic cells. The suggested dipole system is also promising for the accelerated diffusion transfer of magnetic nanoparticles, which are located in a liquid carrier, due to a gradient magnetic field.
    Permanent Link: http://hdl.handle.net/11104/0306060

     
     
Number of the records: 1