Macromolecular conjugates for visualization and separation of proteins and cells

0519462 - ÚOCHB 2020 RIV eng P - Patent Document
Šácha, Pavel - Konvalinka, Jan - Schimer, Jiří - Knedlík, Tomáš - Navrátil, Václav - Tykvart, Jan - Sedlák, František - Majer, Pavel - Cígler, Petr - Šubr, Vladimír - Ulbrich, Karel - Strohalm, Jiří
Macromolecular conjugates for visualization and separation of proteins and cells.
2019. Owner: Ústav organické chemie a biochemie AV ČR, v. v. i. - Ústav makromolekulární chemie AV ČR, v. v. i. - Univerzita Karlova v Praze. Date of the patent acceptance: 09.12.2019. Patent Number: SG11201704995Q
R&D Projects: GA ČR(CZ) GA16-02938S; GA MŠMT LO1302
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetics * flow cytometry * ELISA * protein targeting * polymer conjugates * molecular recognition * HPMA
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)

The present invention describes macromolecular water-soluble conjugates based on synthetic copolymers to which at least one affinity tag, at least one imaging probe and at least one targeting ligand are bound via covalent bonds. The macromolecular conjugate may be used in identification, visualization, quantification or isolation of proteins and/or cells.
Permanent Link: http://hdl.handle.net/11104/0304443