Biological action in and out of the water window

0490027 - FZÚ 2019 RIV PL eng J - Journal Article
Vyšín, Luděk - Davídková, Marie - Wachulak, P. - Fiedorowicz, H. - Bartnik, A. - Krůs, Miroslav - Kozlová, Michaela - Skála, Jiří - Dostál, Jan - Dudžák, Roman - Juha, Libor
Biological action in and out of the water window.
Acta Physica Polonica A. Roč. 133, č. 2 (2018), s. 236-238. ISSN 0587-4246. E-ISSN 1898-794X
R&D Projects: GA MŠMT(CZ) LM2015083; GA MŠMT EF15_008/0000162; GA ČR GA17-05076S; GA ČR(CZ) GBP108/12/G108
EU Projects: European Commission(XE) 654148 - LASERLAB-EUROPE
Grant - others:ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162
Institutional support: RVO:68378271 ; RVO:61389005
Keywords : X-ray pulses * mammalian-cells * DNA * damage
OECD category: Fluids and plasma physics (including surface physics)
Impact factor: 0.545, year: 2018

This study is dealing with the difference of radiation chemical yields of single and double strand breaks induced in plasmid DNA by photons inside and outside of the soft X-ray water window, i.e., in the wavelength range from 2.28 nm to 4.88 nm. Photons were generated by various plasma sources providing nanosecond and sub-nanosecond pulses of extreme ultraviolet, soft X-ray and X-ray radiation. DNA strand breaks were determined by agarose gel electrophoresis. Higher radiation chemical yields of both single and double strand breaks were found using picosecond and nanosecond sources of extreme ultraviolet and X-ray radiation.
Permanent Link: http://hdl.handle.net/11104/0284337