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Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA
- 1.0482517 - ÚOCHB 2018 RIV GB eng J - Journal Article
Balintová, Jana - Simonova, Anna - Bialek-Pietras, M. - Olejniczak, A. - Lesnikowski, Z. J. - Hocek, Michal
Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.
Bioorganic and Medicinal Chemistry Letters. Roč. 27, č. 21 (2017), s. 4786-4788. ISSN 0960-894X. E-ISSN 1464-3405
R&D Projects: GA ČR GBP206/12/G151
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : nucleotides * nucleoside triphosphates * carboranes * DNA polymerase * oligonucleotides
OECD category: Organic chemistry
Impact factor: 2.442, year: 2017
5-[(p-Carborane-2-yl) ethynyl]-2'-deoxyuridine 5'-O-triphosphate was synthesized and used as a good substrate in enzymatic construction of carborane-modified DNA or oligonucleotides containing up to 21 carborane moieties in primer extension reactions by DNA polymerases.
Permanent Link: http://hdl.handle.net/11104/0277943
Number of the records: 1