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Copy-number variation of housekeeping gene rpl13a in rat strains selected for nervous system excitability
- 1.0480079 - BÚ 2018 RIV GB eng J - Journal Article
Kalendar, R. - Belyayev, Alexander - Zachepilo, T. - Vaido, A. - Maidanyuk, D. - Schulman, A. H. - Dyuzhikova, N.
Copy-number variation of housekeeping gene rpl13a in rat strains selected for nervous system excitability.
Molecular and Cellular Probes. Roč. 33, JUN 2017 (2017), s. 11-15. ISSN 0890-8508. E-ISSN 1096-1194
Institutional support: RVO:67985939
Keywords : copy number variation (CNV) * quantitative real-time multicolor multiplex * PCR (qmPCR)
OECD category: Cell biology
Impact factor: 1.689, year: 2017
We evaluated copy number variation (CNV) for four genes in rat strains differing in nervous system excitability. rpl13a copy number is significantly reduced in hippocampus and bone marrow in rats with a high excitability threshold and stress. The observed phenomenon may be associated with a role for rpl13a in lipid metabolism.
Permanent Link: http://hdl.handle.net/11104/0277957
Number of the records: 1