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A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study

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    0473067 - ÚMG 2017 RIV US eng J - Journal Article
    Vernerová, L. - Špoutil, František - Vlček, M. - Kršková, K. - Penesová, A. - Mesková, M. - Marko, A. - Raslová, K. - Vohnout, B. - Rovenský, J. - Killinger, Z. - Jochmanová, I. - Lazurová, I. - Steiner, G. - Smolen, J. - Imrich, R.
    A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.
    PLoS ONE. Roč. 11, č. 4 (2016), č. článku e0153316. ISSN 1932-6203. E-ISSN 1932-6203
    Institutional support: RVO:68378050
    Keywords : genome-wide association * hla-drb1 shared epitope * gene-environment interactions * citrullinated proteins * susceptibility genes * risk loci * cohort * antibodies * progression * population
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 2.806, year: 2016

    The aim of the study was to analyse genetic architecture of RA by utilizing multiparametric statistical methods such as linear discriminant analysis (LDA) and redundancy analysis (RDA).
    Permanent Link: http://hdl.handle.net/11104/0270234

     
     
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