0466409 - ÚPT 2017 RIV DE eng C - Conference Paper (international conference)
Dražanová, Eva - Rudá, J. - Krátká, Lucie - Horská, K. - Kotolová, H. - Babinská, Z. - Starčuk jr., Zenon
The influence of chronic application of olazapin on brain perfusion in rat.
Magma. Vol. 29 S1. Berlin: Springer, 2016, s. 448-449. E-ISSN 1352-8661.
[ESMRMB 2016 Congress. Vienna (AT), 29.09.2016-01.10.2016]
R&D Projects: GA MŠMT(CZ) LO1212
Institutional support: RVO:68081731
Keywords : arterial spin labeling * ASL * olanzapin
Subject RIV: BM - Solid Matter Physics ; Magnetism
Result website:
http://link.springer.com/journal/10334/29/1/suppl/page/1

Olanzapin is a commonly used atypical antipsychotic drug. We hypothesize that long term therapy of olanzapin could alter region dependent blood brain perfusion, which we tested by arterial spin labeling (ASL) MR imaging.
Statistical evaluation of the ASL results in the hippocampus, somatosensory cortex and piriform cortex revealed significantly lower somatosensory cortex perfusion in olanzapin-treated animals.
Permanent Link: http://hdl.handle.net/11104/0264771