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Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance
- 1.0466229 - ÚMCH 2017 RIV NL eng J - Journal Article
Braunová, Alena - Kostka, Libor - Sivák, Ladislav - Cuchalová, Lucie - Hvězdová, Zuzana - Laga, Richard - Filippov, Sergey K. - Černoch, Peter - Pechar, Michal - Janoušková, Olga - Šírová, Milada - Etrych, Tomáš
Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance.
Journal of Controlled Release. Roč. 245, 10 January (2017), s. 41-51. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA MZd(CZ) NV16-28600A; GA MŠMT(CZ) LO1507; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : multidrug resistance * P-glycoprotein inhibitor * EPR effect
OECD category: Polymer science; Microbiology (MBU-M)
Impact factor: 7.877, year: 2017
New amphiphilic diblock polymer nanotherapeutics serving simultaneously as a drug delivery system and an inhibitor of multidrug resistance were designed, synthesized, and evaluated for their physico-chemical and biological characteristics.
Permanent Link: http://hdl.handle.net/11104/0264763
Number of the records: 1