Number of the records: 1
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors
- 1.0455915 - BC 2016 RIV US eng J - Journal Article
Fajtová, P. - Štefanić, S. - Hradilek, M. - Dvořák, Jan - Vondrášek, J. - Jílková, A. - Ulrychová, L. - McKerrow, J.H. - Caffrey, C.R. - Mareš, M. - Horn, M.
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
PLoS Neglected Tropical Diseases. Roč. 9, č. 6 (2015), e0003827. ISSN 1935-2735. E-ISSN 1935-2735
Institutional support: RVO:60077344
Keywords : Schistosoma mansoni * schistosomiasis * prolyl oligopeptidase * blood fluke
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.948, year: 2015
Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl oligopeptidase (SmPOP) from the serine peptidase family S9, which has not been investigated in detail in trematodes.
Permanent Link: http://hdl.handle.net/11104/0256550
Number of the records: 1