The combination of meltblown and electrospinning for bone tissue engineering

0452110 - ÚEM 2016 RIV NL eng J - Journal Article
Erben, J. - Pilařová, K. - Sanetrník, F. - Chvojka, J. - Jenčová, V. - Blažková, L. - Havlíček, J. - Novák, O. - Mikeš, P. - Prosecká, Eva - Lukáš, D. - Kuželová Kostaková, E.
The combination of meltblown and electrospinning for bone tissue engineering.
Materials Letters. Roč. 143, mar 15 (2015), s. 172-176. ISSN 0167-577X. E-ISSN 1873-4979
Institutional support: RVO:68378041
Keywords : meltblown * electrospinning * tissue engineering * polycaprolactone
Subject RIV: JI - Composite Materials
Impact factor: 2.437, year: 2015

Materials combining meltblown and electrospinning products with hydroxyapatite powder as potential scaffolds for bone tissue engineering are presented here. The combination of these technologies and parameters and final micro-nanofibrous products are introduced too. The in-vitro testing compared meltblown material, meltblown material with sputtered particles, meltblown material combined with electrospun fibers, meltblown material combined with electrospun fibers and sputtered particles. All the fibrous materials are produced from polycaprolactone. The first in-vitro tests showed the high potential of developed composite materials in bone tissue engineering. The structure of the tested materials allows osteoblasts to proliferate into the sample inner structure with the significant contribution of nanofiber content to cell proliferation. (C) 2015 Elsevier B.V. All rights reserved.
Permanent Link: http://hdl.handle.net/11104/0253133