Frontiers in Clinical Drug Research: Anti-Infectives

0451027 - ÚIACH 2017 RIV AE eng M - Monography Chapter
Horká, Marie - Kubesová, Anna - Moravcová, Dana - Šalplachta, Jiří - Šesták, Jozef - Tesařová, Marie - Růžička, F.
Identification of Nosocomial Pathogens and Antimicrobials Using Phenotypic Techniques.
Frontiers in Clinical Drug Research: Anti-Infectives. Volume 2. Sharjah: Bentham Science Publishers, 2016 - (Atta-ur-Rahman), s. 151-203. ISBN 978-1-68108-154-0
R&D Projects: GA MV VG20112015021; GA MV VG20102015023
Institutional support: RVO:68081715
Keywords : antibiotics and antifungals * capillary electrophoretic techniques * microorganisms * nosocomial infections
Subject RIV: CB - Analytical Chemistry, Separation

Nosocomial infections caused by multidrug-resistant strains increase morbidity and mortality in hospitalized patients, prolong hospitalization, and they have significant negative economic impact. Currently, nosocomial infections are included in a broader concept as healthcare-associated infections. These are caused by a wide variety of pathogens, typically Staphylococci, Enterococci, Pseudomonas aeruginosa, Klebsiella spp., Escherichia coli, etc. Certain fungal agents, e.g., yeasts of Candida genus and aspergilla, are also associated with these infections. The situation is further complicated by the development of resistance in the gram-positive cocci such as staphylococci or enterococci to second-line antibiotics used for the treatment of gramnegative bacteria and resistant gram-positive bacteria. Pathogenesis of mentioned infections plays a key role in forming biofilms on artificial surfaces.
Permanent Link: http://hdl.handle.net/11104/0252211