Organ weight changes in mice after long-term inhalation exposure to manganese oxides nanoparticles

0448899 - ÚIACH 2016 RIV GB eng J - Journal Article
Zeman, T. - Buchtová, Marcela - Dočekal, Bohumil - Míšek, Ivan - Navrátil, J. - Mikuška, Pavel - Šerý, Omar - Večeřa, Zbyněk
Organ weight changes in mice after long-term inhalation exposure to manganese oxides nanoparticles.
Journal of Physics: Conference Series. Roč. 617, č. 012018 (2015), s. 1-6. ISSN 1742-6588. E-ISSN 1742-6596.
[International Conference on Safe Production and Use of Nanomaterials (Nanosafe2014) /4./. Grenoble, 18.11.2014-20.11.2014]
R&D Projects: GA ČR(CZ) GBP503/12/G147; GA ČR(CZ) GAP503/11/2315
Institutional support: RVO:68081715 ; RVO:67985904
Keywords : nanoparticles * inhalation * mice
Subject RIV: CB - Analytical Chemistry, Separation

A long-term inhalation experiment on laboratory mice was performed to assess the effect of inhaled manganese oxides nanoparticles on weight of internal organs. It was discovered that the resulting change in weight of selected organs is disproportional. The mice from the experimental group had statistically significantly lighter kidneys, liver and spleen and heavier pancreas compared to the mice from the control group.
Permanent Link: http://hdl.handle.net/11104/0250494