Simple flow-focusing microfluidic chip for droplet generation

0448873 - ÚIACH 2016 RIV CZ eng C - Conference Paper (international conference)
Křivánková, Jana - Basova, E. Y. - Foret, František
Simple flow-focusing microfluidic chip for droplet generation.
CECE 2015. 12th International Interdisciplinary Meeting on Bioanalysis. Brno: Ústav analytické chemie AV ČR, v. v. i, 2015 - (Foret, F.; Křenková, J.; Drobníková, I.; Klepárník, K.), s. 127-129. ISBN 978-80-904959-3-7.
[CECE 2015. International Interdisciplinary Meeting on Bioanalysis /12./. Brno (CZ), 21.09.2015-23.09.2015]
R&D Projects: GA ČR(CZ) GBP206/12/G014
Institutional support: RVO:68081715
Keywords : microfluidic chip * droplet generation * fluorinated oil phase
Subject RIV: CB - Analytical Chemistry, Separation
http://www.ce-ce.org/CECE2015/CECE%202015%20proceedings_full.pdf

There is an ascending requirement for analysis of chemical content of individual cells involving combination of various bioanalytical and optical sensors and arrangements. At the beginning of the cell analysis there is a need for creation of suitable transport vessels - droplets - that can be easily counted, sorted and serve for manipulation of cells with preserved biocompability as well. Among all of bioanalytical approaches droplet-based microfluidics proved its potential for producing droplets with precisely controlled size, shape as well as for encapsulation of reactants and delivering drugs. This study presents a simple microfluidic chip with flow-focusing geometry for generation of water droplets in fluorocarbon oil.
Permanent Link: http://hdl.handle.net/11104/0250470