Number of the records: 1
Two SAPP2 gene homologs are present in Candida parapsilosis genome
- 1.0446961 - ÚOCHB 2016 RIV CZ eng J - Journal Article
Dostál, Jiří - Merkerová, M. - Vinterová, Zuzana - Pichová, Iva - Hrušková-Heidingsfeldová, Olga
Two SAPP2 gene homologs are present in Candida parapsilosis genome.
Folia Microbiologica. Roč. 60, č. 5 (2015), s. 373-374. ISSN 0015-5632. E-ISSN 1874-9356
R&D Projects: GA ČR(CZ) GA14-23022S; GA MŠMT LO1302
Institutional support: RVO:61388963
Keywords : aspartic proteinases * Candida parapsilosis * opportunistic pathogen
Subject RIV: EE - Microbiology, Virology
Impact factor: 1.335, year: 2015
Candida parapsilosis produces secreted aspartic proteinases (Saps), which contribute to the virulence of this opportunistic pathogen. Gene family containing as many as 14 sequences potentially encoding secreted aspartic proteinases was identified in C. parapsilosis genome. Of them, SAPP1 and SAPP2 genes have been extensively characterized, but only now do we report that two SAPP2 homologs sharing 91.5% identity occur in C. parapsilosis genome. Existence of SAPP2 homologs points to unexpected complexity of the SAPP gene family.
Permanent Link: http://hdl.handle.net/11104/0248930
Number of the records: 1