Optimization and preparation of FRET-based sensor for detection of DNA mutations

0446728 - ÚIACH 2016 GB eng A - Abstract
Datinská, Vladimíra - Týčová, Anna - Klepárník, Karel - Belšánová, B. - Minárik, M. - Foret, František
Optimization and preparation of FRET-based sensor for detection of DNA mutations.
4th International Conference on Bio-Sensing Technology 2015 (BITE2015). Elsevier, 2015. s. 2.058.
[International Conference on Bio-Sensing Technology /4./. 10.05.2015-13.05.2015, Lisbon]
R&D Projects: GA TA ČR(CZ) TA02010672; GA ČR(CZ) GA14-28254S
Institutional support: RVO:68081715
Keywords : FRET * quantum dot * DNA
Subject RIV: CB - Analytical Chemistry, Separation
https://elsevier.conference-services.net/secureProgramme.asp?conferenceID=3808&uID=703758&action=secure_prog_titles

In this study, a new FRET-based sensor for detection of DNA mutation is demonstrated. The sensor is based on energy transfer between a laboratory synthesized quantum dot (donor) and fluorescence dye ROX (acceptor), attached to complementary ssDNA molecules.
Permanent Link: http://hdl.handle.net/11104/0248706