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histoneHMM: Differential analysis of histone modifications with broad genomic footprints

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    0443201 - FGÚ 2016 RIV GB eng J - Journal Article
    Heinig, M. - Colomé-Tatché, M. - Taudt, A. - Rintisch, C. - Schafer, S. - Pravenec, Michal - Hubner, N. - Vingron, M. - Johannes, F.
    histoneHMM: Differential analysis of histone modifications with broad genomic footprints.
    BMC Bioinformatics. Roč. 16, Feb 22 (2015), s. 60. ISSN 1471-2105. E-ISSN 1471-2105
    R&D Projects: GA MŠMT(CZ) 7E10067; GA ČR(CZ) GA13-04420S
    Institutional support: RVO:67985823
    Keywords : ChIP-seq * histone modifications * Hidden Markov model * computational biology * differential analysis
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 2.435, year: 2015

    histoneHMM is a fast algorithm written in C++ and compiled as an R package. It runs in the popular R computing environment and thus seamlessly integrates with the extensive bioinformatic tool sets available through Bioconductor. This makes histoneHMM an attractive choice for the differential analysis of ChIP-seq data. Software is available from http://histonehmm.molgen.mpg.de
    Permanent Link: http://hdl.handle.net/11104/0245945

     
     
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