Posttranslational modifications of lysine and evolving role in heart pathologies - Recent developments

0442314 - ÚIACH 2015 RIV DE eng J - Journal Article
Šťastná, Miroslava - Van Eyk, J.E.
Posttranslational modifications of lysine and evolving role in heart pathologies - Recent developments.
Proteomics. Roč. 15, 5-6 (2015), s. 1164-1180. ISSN 1615-9853. E-ISSN 1615-9861
Institutional support: RVO:68081715
Keywords : heart pathologies * neddylation * sumoylation * proteomics
Subject RIV: CB - Analytical Chemistry, Separation
Impact factor: 4.079, year: 2015

We discuss the PTMs that occur on lysine, specifically neddylation and sumoylation, and the proteomic approaches that can be applied for identification and quantification. Of interest are the emerging roles for these modifications in heart disease and what can be inferred from studies in other cell types and organs.
Permanent Link: http://hdl.handle.net/11104/0245145