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Indoor air pollution exposure from use of indoor stoves and fireplaces in association with breast cancer: a case-control study
- 1.0440505 - ÚEM 2015 RIV GB eng J - Journal Article
White, A. J. - Teitelbaum, S. L. - Stellman, S. D. - Beyea, J. - Steck, S. E. - Mordukhovich, I. - McCarty, K. M. - Ahn, J. - Rössner ml., Pavel - Santella, R. M. - Gammon, M. D.
Indoor air pollution exposure from use of indoor stoves and fireplaces in association with breast cancer: a case-control study.
Environmental Health: A Global Access Science Source. Roč. 13, Dec 12 (2014), s. 108. E-ISSN 1476-069X
Institutional support: RVO:68378041
Keywords : polycyclic aromatic hydrocarbons * GST * cancer
Subject RIV: DN - Health Impact of the Environment Quality
Impact factor: 3.372, year: 2014
The cells were treated for 24 h with B[a]P (1 μM, 10 μM, 25 μM) and EOMs (1 μg/ml, 10 μg/ml, 25 μg/ml). 25 μM of B[a]P and most of the tested doses of EOMs induced double strand breaks (DSBs) as indicated by H2AX phosphorylation. DNA damage was accompanied by induction of XRCC4 expression and an increased frequency of chromosomal aberrations. Translocations most frequently affected chromosome 7. We observed only a weak induction of Ku70/80 expression as well as ligation activity of nuclear extracts.
Permanent Link: http://hdl.handle.net/11104/0243915
Number of the records: 1