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Research Methodology in Physics and Chemistry of Surfaces and Interfaces

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    0434993 - ÚMCH 2015 RIV CA eng M - Monography Chapter
    Horák, Daniel - Hlídková, Helena
    Pore structure of poly(2-hydroxyethyl methacrylate) scaffolds.
    Research Methodology in Physics and Chemistry of Surfaces and Interfaces. Oakville: Apple Academic Press, 2014 - (Guarrotxena, N.), s. 79-99. ISBN 978-1-77188-011-4
    R&D Projects: GA ČR GAP304/11/0731
    Institutional support: RVO:61389013
    Keywords : hydrogels * low-vacuum scanning electron mMicroscopy * poly(2-hydroxyethyl methacrylate)
    Subject RIV: FH - Neurology
    http://www.appleacademicpress.com/title.php?id=9781771880114

    Polymer supports have received much attention as a microenvironment for cell adhesion, proliferation, migration, and differentiation in tissue engineering and regenerative medicine. The three-dimensional scaffold structure provides support for high level of tissue organization and remodeling. Regeneration of different tissues, such as bone, cartilage, skin, nerves, or blood vessels, is investigated using such constructs. Superporous PHEMA constructs were prepared by bulk radical copolymerization of HEMA and EDMA in the presence of NaCl or/and liquid diluent (CyOH/DOH) or (NH4)2SO4 crystals. Morphology of the prepared scaffolds was characterized by several methods including scanning electron microscopy both in swollen (LVSEM) and dry (HVSEM) state, solvent (water and cyclohexane) regains, high- and low-pressure mercury porosimetry of lyophilized samples, and dynamic desorption of nitrogen.
    Permanent Link: http://hdl.handle.net/11104/0238929

     
     
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