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Fluconazole affects the alkali-metal-cation homeostasis and susceptibility to cationic toxic compounds of Candida glabrata
- 1.0431290 - FGÚ 2015 RIV GB eng J - Journal Article
Elicharová, Hana - Sychrová, Hana
Fluconazole affects the alkali-metal-cation homeostasis and susceptibility to cationic toxic compounds of Candida glabrata.
Microbiology. Roč. 160, č. 8 (2014), s. 1705-1713. ISSN 1350-0872. E-ISSN 1465-2080
R&D Projects: GA ČR GAP302/12/1151; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : Candida glabrata * fluconazole * membrane potential
Subject RIV: EE - Microbiology, Virology
Impact factor: 2.557, year: 2014
We analyze the contribution of plasma-membrane alkali-metal-cation exporters, a cation/proton antiporter and a cation ATPase, to cation homeostasis and the maintenance of membrane potential and we show that we show that the combination of subinhibitory concentrations of fluconazole and cationic drugs strongly affects the growth of C. glabrata cells
Permanent Link: http://hdl.handle.net/11104/0235897
Number of the records: 1