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Fluorescent Nanodiamonds with Bioorthogonally Reactive Protein-Resistant Polymeric Coatings
- 1.0429976 - ÚOCHB 2015 RIV DE eng J - Journal Article
Řehoř, Ivan - Macková, Hana - Filippov, Sergey K. - Kučka, Jan - Proks, Vladimír - Šlegerová, Jitka - Turner, S. - van Tendeloo, G. - Ledvina, Miroslav - Hrubý, Martin - Cígler, Petr
Fluorescent Nanodiamonds with Bioorthogonally Reactive Protein-Resistant Polymeric Coatings.
ChemPlusChem. Roč. 79, č. 1 (2014), s. 21-24. ISSN 2192-6506. E-ISSN 2192-6506
R&D Projects: GA ČR GAP108/12/0640; GA MŠMT(CZ) LH11027
Grant - others:OPPK(CZ) CZ.2.16/3.1.00/24016; Seventh Framework Programme of the European Union(XE) FP7-262348; European Research Council(XE) FP7-246791
Institutional support: RVO:61388963 ; RVO:61389013 ; RVO:61389005
Keywords : click chemistry * fluorescence * nanoparticles * polymerization * solubilization
Subject RIV: CC - Organic Chemistry; CD - Macromolecular Chemistry (UMCH-V)
Impact factor: 3.026, year: 2014
The novel synthesis of a polymeric interface grown from the surface of bright fluorescent nanodiamonds is reported. The polymer enables bioorthogonal attachment of various molecules by click chemistry; the particles are resistant to nonspecific protein adsorption and show outstanding colloidal stability in buffers and biological media. The coating fully preserves the unique optical properties of the nitrogen-vacancy centers that are crucial for bioimaging and sensoric applications.
Permanent Link: http://hdl.handle.net/11104/0235046
Number of the records: 1