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Update on the role of spinal cord TRPV1 receptors in pain modulation

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    0428034 - FGÚ 2015 RIV CZ eng J - Journal Article
    Špicarová, Diana - Nerandžič, Vladimír - Paleček, Jiří
    Update on the role of spinal cord TRPV1 receptors in pain modulation.
    Physiological Research. Roč. 63, Suppl.1 (2014), S225-S236. ISSN 0862-8408. E-ISSN 1802-9973
    R&D Projects: GA ČR(CZ) GA305/09/1228; GA MŠMT(CZ) LH12058; GA ČR(CZ) GBP304/12/G069; GA ČR(CZ) GPP303/12/P510
    Grant - others:Univerzita Karlova(CZ) 309211
    Institutional support: RVO:67985823
    Keywords : hyperalgesia * capsaicin * TRPV1 * Spinal cord
    Subject RIV: FH - Neurology
    Impact factor: 1.293, year: 2014

    The structure, expression and function of the transient receptor potential vanilloid 1 (TRPV1) receptor were intensively studied since the cloning in 1997 and TRPV1 receptors are now considered to act as transducers and molecular integrators of nociceptive stimuli in the periphery. In contrast, spinal TRPV1 receptors were studied less extensively and their role in pain modulation is still not fully understood. This short review is a follow up on our previous summary in this area (Spicarova and Palecek 2008)
    Permanent Link: http://hdl.handle.net/11104/0233477

     
     
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