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New sensor for DNA mutation detection

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    0422677 - ÚIACH 2014 RIV CZ eng C - Conference Paper (international conference)
    Datinská, Vladimíra - Klepárník, Karel - Minárik, M. - Foret, František
    New sensor for DNA mutation detection.
    Chemické Listy. Roč. 107, Issue s3.. Praha: Česká společnost chemická, 2013, s. 301. ISSN 0009-2770. E-ISSN 1213-7103.
    [CECE Junior 2013. Brno (CZ), 12.11.2013-13.11.2013]
    R&D Projects: GA MŠMT(CZ) EE2.3.20.0182; GA TA ČR(CZ) TA02010672
    Institutional support: RVO:68081715
    Keywords : quantum dots * Förster resonance energy transfer * CE-LIF
    Subject RIV: CB - Analytical Chemistry, Separation

    We present a design and synthesis of a new sensor intended for the genomic analysis in molecular cancer research. This sensor is based on the Förster resonance energy transfer (FRET) and can be used for the detection of complementary oligonucletide chains based on probe hybridization. Quantum dots (QDs) with their unique optical properties serve as suitable donors of energy in FRET.
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    20130130.pdf9240.7 KBPublisher’s postprintrequire
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