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Surface plasmon resonance sensing of nucleic acids: A review

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    0396514 - ÚFE 2014 RIV NL eng J - Journal Article
    Šípová, Hana - Homola, Jiří
    Surface plasmon resonance sensing of nucleic acids: A review.
    Analytica Chimica Acta. -, č. 773 (2013), s. 9-23. ISSN 0003-2670. E-ISSN 1873-4324
    R&D Projects: GA MŠMT(CZ) LH11102
    Institutional support: RVO:67985882
    Keywords : Surface plasmon resonance * Nucleic acid * Biosensor
    Subject RIV: JB - Sensors, Measurment, Regulation
    Impact factor: 4.517, year: 2013

    Biosensors based on surface plasmon resonance (SPR) have become a central tool for the investigation and quantification of biomolecules and their interactions. Nucleic acids (NAs) play a vital role in numerous biological processes and therefore have been one of the major groups of biomolecules targeted by the SPR biosensors. This paper discusses the advances of NA SPR biosensor technology and reviews its applications both in the research of molecular interactions involving NAs (NA-NA, NA-protein, NA-small molecule), as well as for the field of bioanalytics in the areas of food safety, medical diagnosis and environmental monitoring.
    Permanent Link: http://hdl.handle.net/11104/0224284

     
     
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