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Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde
- 1.0396311 - ÚEM 2014 RIV FI eng J - Journal Article
Mušák, L. - Šmerhovský, Z. - Halásová, E. - Osina, O. - Letková, L. - Vodičková, Ludmila - Poláková, Veronika - Buchancová, J. - Hemminki, K. - Vodička, Pavel
Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde.
Scandinavian Journal of Work Environment & Health. Roč. 39, č. 6 (2013), s. 618-630. ISSN 0355-3140. E-ISSN 1795-990X
Grant - others:MŠVV(SK) 26220220111; UK(SK) 1/0576/10 VEGA; MZd(SK) 2007/48-UK-13; GA MŠMT(CZ) Prvouk-P27/LF1/1
Institutional support: RVO:68378041
Keywords : anesthesiologist * antineoplastic drug * chromosomal aberration
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.095, year: 2013
Structural chromosomal aberrations in blood lymphocytes represent a biomarker for cellular damage caused by genotoxic carcinogens and are an indicator of increased cancer risk. Stratified data analysis showed the risk of increased chromosomal aberrations among non-smoking female nurses and physi¬cians exposed to anesthetics, cytostatics and, partially, formaldehyde. Chromatid and chromosome exchanges were significantly higher in the exposed groups than among controls.
Permanent Link: http://hdl.handle.net/11104/0225707
Number of the records: 1