Single cell analysis: State of the art

0395853 - ÚIACH 2014 HU eng A - Abstract
Klepárník, Karel
Single cell analysis: State of the art.
CECE 2013. Program and Abstract Book. University of Pécs, 2013 - (Kilár, F.; Nagy, L.; Kiss, I.). s. 53-53. ISBN 978-963-642-517-3.
[CECE 2013. International Interdisciplinary Meeting on Bioanalysis /10./. 25.04.2013-27.04.2013, Pécs]
R&D Projects: GA MŠMT(CZ) EE2.3.20.0182; GA ČR(CZ) GBP206/12/G014; GA ČR GAP206/11/2377
Institutional support: RVO:68081715
Keywords : single cell analysis * individual cells * specific probes
Subject RIV: CB - Analytical Chemistry, Separation

In this talk, more than a quarter of century long history of SCA will be overviewed. Throughout this period, it has been demonstrated that miniaturized capillary or microfluidic devices furnished with advanced detection methods provide suitable conditions for the analysis of chemical content of individual cells, cell organelles or even detecting single molecules. The recent development of nanotechnologies brings new extraordinary opportunities into the practice of analytical chemistry. The combination of specific probes, labels and sensors with powerful and stable light sources, advanced optical arrangements and high-sensitivity detectors allows detecting and tracking even single molecules with nanometer spatial precision and millisecond time resolution in living cells.
Permanent Link: http://hdl.handle.net/11104/0223745