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Stem Cells in Regenerative Medicine
- 1.0394729 - ÚEM 2014 RIV JP eng J - Journal Article
Syková, Eva - Forostyak, Serhiy
Stem Cells in Regenerative Medicine.
Laser Therapy. Roč. 22, č. 2 (2013), s. 87-92. ISSN 0898-5901
R&D Projects: GA ČR(CZ) GAP304/11/0189; GA ČR(CZ) GBP304/12/G069
Institutional research plan: CEZ:AV0Z50390703
Institutional support: RVO:68378041
Keywords : cell therapy * stem cells * clinical study
Subject RIV: FH - Neurology
A number of cardiovascular, neurological, musculoskeletal and other diseases have a limited capacity for repair and only a modest progress has been made in treatment of brain diseases. The discovery of stem cells has opened new possibilities for the treatment of these maladies, and cell therapy now stands at the cutting-edge of modern regenerative medicine and tissue engineering. Here, we briefly review the main achievements and trends in cell-based therapy, with an emphasis on the main types of stem cells: embryonic, mesenchymal stromal and induced pluripotent cells. We discuss questions regarding the application of stem cells, particularly tumorigenicity, immune rejection and danger of gene manipulation. Currently, only MSC seems to be safe and might be considered to be a leading candidate for human application to treat pathologies that affect the cardiovascular, neurological and musculoskeletal systems.
Permanent Link: http://hdl.handle.net/11104/0224294
Number of the records: 1