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Short-term fasting reduces the extent of myocardial infarction and incidence of reperfusion arrhythmias in rats

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    0389397 - FGÚ 2013 RIV CZ eng J - Journal Article
    Šnorek, M. - Hodyc, D. - Šedivý, V. - Ďurišová, J. - Skoumalová, A. - Wilhelm, J. - Neckář, Jan - Kolář, František - Herget, J.
    Short-term fasting reduces the extent of myocardial infarction and incidence of reperfusion arrhythmias in rats.
    Physiological Research. Roč. 61, č. 6 (2012), s. 567-574. ISSN 0862-8408. E-ISSN 1802-9973
    R&D Projects: GA MŠMT(CZ) 1M0510; GA ČR(CZ) GA305/08/0108
    Institutional research plan: CEZ:AV0Z5011922
    Keywords : myocardial ischemia/reperfusion * arrhythmias * infarction * fasting * ketone bodies
    Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery
    Impact factor: 1.531, year: 2012

    The effect of three-day fasting on cardiac ischemic tolerance was investigated in adult male Wistar rats. Our study shown that fasting effectively protected rat hearts against major endpoints of acute ischemia/reperfusion injury. Further studies are needed to find out whether these beneficial effects can be linked to altered mitochondrial redox state resulting from increased ketogenesis
    Permanent Link: http://hdl.handle.net/11104/0218291

     
     
Number of the records: 1  

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