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Transcriptional regulation of the operon encoding stress-responsive ECF sigma factor SigH and its anti-sigma factor RshA, and control of its regulatory network in Corynebacterium glutamicum
- 1.0387740 - MBÚ 2013 RIV GB eng J - Journal Article
Busche, T. - Šilar, Radoslav - Pičmanová, Martina - Pátek, Miroslav - Kalinowski, J.
Transcriptional regulation of the operon encoding stress-responsive ECF sigma factor SigH and its anti-sigma factor RshA, and control of its regulatory network in Corynebacterium glutamicum.
BMC Genomics. Roč. 13, č. 445 (2012), s. 445-464. ISSN 1471-2164. E-ISSN 1471-2164
R&D Projects: GA ČR GC204/09/J015
Institutional research plan: CEZ:AV0Z50200510
Keywords : Corynebacterium glutamicum * ECF sigma factor * Anti-sigma factor
Subject RIV: EE - Microbiology, Virology
Impact factor: 4.397, year: 2012
Background: The expression of genes in Corynebacterium glutamicum, a Gram-positive non-pathogenic bacterium used mainly for the industrial production of amino acids, is regulated by seven different sigma factors of RNA polymerase, including the stress-responsive ECF-sigma factor SigH. The sigH gene is located in a gene cluster together with the rshA gene, putatively encoding an anti-sigma factor. The aim of this study was to analyze the transcriptional regulation of the sigH and rshA gene cluster and the effects of RshA on the SigH regulon, in order to refine the model describing the role of SigH and RshA during stress response
Permanent Link: http://hdl.handle.net/11104/0220331
Number of the records: 1