0384562 - ÚMCH 2013 RIV DE eng J - Journal Article
Filippov, Sergey K. - Sedláček, Ondřej - Bogomolova, Anna - Vetrík, Miroslav - Jirák, D. - Kovář, J. - Kučka, Jan - Bals, S. - Turner, S. - Štěpánek, Petr - Hrubý, Martin
Glycogen as a biodegradable construction nanomaterial for in vivo use.
Macromolecular Bioscience. Roč. 12, č. 12 (2012), s. 1731-1738. ISSN 1616-5187. E-ISSN 1616-5195
R&D Projects: GA ČR GA202/09/2078; GA ČR GAP108/12/0640; GA ČR GAP208/10/1600; GA ČR GPP207/10/P054
Institutional research plan: CEZ:AV0Z40500505
Institutional support: RVO:61389013
Keywords : nanoparticles * in vivo imaging * glycogen
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 3.742, year: 2012 ; AIS: 0.965, rok: 2012
DOI: https://doi.org/10.1002/mabi.201200294

It is demonstrated that glycogen as a biodegradable and inexpensive material coming from renewable resources can be used as a carrier for the construction of in vivo imaging nanoagents. The model system considered is composed of glycogen modified with gadolinium and fluorescent labels. Systematic studies of properties of these nanocarriers by a variety of physical methods and results of in vivo tests of biodegradability are reported.
Permanent Link: http://hdl.handle.net/11104/0216064