Number of the records: 1
Spatial Navigation and APOE in Amnestic Mild Cognitive Impairment
- 1.0370885 - FGÚ 2012 RIV CH eng J - Journal Article
Laczó, J. - Andel, R. - Vlček, Kamil - Maťoška, V. - Vyhnálek, M. - Tolar, M. - Bojar, M. - Hort, J.
Spatial Navigation and APOE in Amnestic Mild Cognitive Impairment.
Neurodegenerative Diseases. Roč. 8, č. 4 (2011), s. 169-177. ISSN 1660-2854. E-ISSN 1660-2862
R&D Projects: GA ČR(CZ) GA309/09/0286; GA ČR(CZ) GA309/09/1053; GA MŠMT(CZ) 1M0517; GA MŠMT(CZ) LC554
Institutional research plan: CEZ:AV0Z50110509
Keywords : mild cognitive impairment * spatial navigation * Alzheimer's disease
Subject RIV: FH - Neurology
Impact factor: 3.056, year: 2011
We found more profound deficits in spatial navigation in aMCI E4 positive relative to aMCI E4 negative patients. The aMCI E4 positive group resembled the mild AD group in spatial navigation performance. Although E4 genotype was indicative of spatial navigation performance, it was not indicative of the aMCI patients’ ability to learn the tasks. Spatial navigation testing represents a promising area with respect to identifying individuals at higher risk for AD among the heterogeneous MCI population
Permanent Link: http://hdl.handle.net/11104/0204561
Number of the records: 1