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Structural basis for DNA recognition by FOXO proteins
- 1.0369959 - FGÚ 2012 RIV NL eng J - Journal Article
Obšil, T. - Obšilová, Veronika
Structural basis for DNA recognition by FOXO proteins.
Biochimica Et Biophysica Acta-Molecular Cell Research. Roč. 1813, č. 11 (2011), s. 1946-1953. ISSN 0167-4889. E-ISSN 1879-2596
R&D Projects: GA AV ČR(CZ) IAA501110801; GA ČR(CZ) GAP207/11/0455; GA MŠMT(CZ) LC554
Grant - others:GA ČR(CZ) GAP305/11/0708
Institutional research plan: CEZ:AV0Z50110509
Keywords : forkhead * FOXO * DNA * structure * DNA recognition
Subject RIV: CE - Biochemistry
Impact factor: 5.538, year: 2011
The FOXO forkhead transcription factors are involved in metabolism control, cell survival, cellular proliferation DNA damage repair response, and stress resistance. The aim of this review is to summarize the recent structural characterization of FOXO proteins, the mechanisms of DNA recognition and the role of posttranslational modifications in the regulation of FOXO DNA-binding properties
Permanent Link: http://hdl.handle.net/11104/0203896
Number of the records: 1