Biotransformation of (1S)-2-Carene and (1S)-3-Carene by Picea abies Suspension Culture

0369831 - ÚEB 2012 RIV CH eng J - Journal Article
Dvořáková, Marcela - Valterová, Irena - Šaman, David - Vaněk, Tomáš
Biotransformation of (1S)-2-Carene and (1S)-3-Carene by Picea abies Suspension Culture.
Molecules. Roč. 16, č. 12 (2011), s. 10541-10555. E-ISSN 1420-3049
R&D Projects: GA MŠMT ME08070; GA MŠMT 2B08058
Institutional research plan: CEZ:AV0Z50380511; CEZ:AV0Z40550506
Keywords : biotransformation * carene * oxidation
Subject RIV: ED - Physiology
Impact factor: 2.386, year: 2011

Biotransformation of (1S)-2-carene and (1S)-3-carene by Picea abies suspension culture led to the formation of oxygenated products. (1S)-2-Carene was transformed slowly and the final product was identified as (1S)-2-caren-4-one. On the other hand, the transformation of (1S)-3-carene was rapid and finally led to the formation of (1S)-3-caren-5-one and (1S)-2-caren-4-one as equally abundant major products. The time-course of the reaction indicates that some products abundant at the beginning of the reaction (e.g. (1S,3S,4R)-3,4-epoxycarane and (1R)-p-mentha-1(7),2-dien-8-ol) were consumed by a subsequent transformations. Thus, a precise selection of the biotransformation time may be used for a production of specific compounds.
Permanent Link: http://hdl.handle.net/11104/0203806