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Anthraquinone as a Redox Label for DNA: Synthesis, Enzymatic Incorporation, and Electrochemistry of Anthraquinone-Modified Nucleosides, Nucleotides, and DNA

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    0369208 - ÚOCHB 2012 RIV DE eng J - Journal Article
    Balintová, Jana - Pohl, Radek - Horáková Brázdilová, Petra - Vidláková, Pavlína - Havran, Luděk - Fojta, Miroslav - Hocek, Michal
    Anthraquinone as a Redox Label for DNA: Synthesis, Enzymatic Incorporation, and Electrochemistry of Anthraquinone-Modified Nucleosides, Nucleotides, and DNA.
    Chemistry - A European Journal. Roč. 17, č. 50 (2011), s. 14063-14073. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA MŠMT(CZ) LC06035; GA MŠMT LC512; GA AV ČR(CZ) IAA400040901
    Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Keywords : anthraquinone * DNA * electrochemistry * nucleosides * oligonucleotides
    Subject RIV: CC - Organic Chemistry
    Impact factor: 5.925, year: 2011

    Anthraquinone-modified nucleotides were prepared and enzymatically incorpoarted to DNA. The anthraquinone served as an excellent redox label for electrochemical detection. The possibility of its combination with another redox label, nitrophenyl group, has been studied.
    Permanent Link: http://hdl.handle.net/11104/0203331

     
     
Number of the records: 1  

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