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Human galectins induce conversion of dermal fibroblasts into myofibroblasts and production of extracellular matrix: potential application in tissue engineering and wound repair

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    0368629 - ÚEM 2012 RIV CH eng J - Journal Article
    Dvořánková, B. - Szabo, P. - Lacina, L. - Gál, P. - Uhrová, J. - Zima, T. - Kaltner, H. - André, S. - Gabius, H. J. - Syková, Eva - Smetana Jr., K.
    Human galectins induce conversion of dermal fibroblasts into myofibroblasts and production of extracellular matrix: potential application in tissue engineering and wound repair.
    Cells Tissues Organs. Roč. 194, č. 6 (2011), s. 469-480. ISSN 1422-6405. E-ISSN 1422-6421
    Grant - others:GA MŠk(CZ) 1M0538
    Program: 1M
    Institutional research plan: CEZ:AV0Z50390703
    Keywords : extracellular matrix * fibronectin * keratinocyte
    Subject RIV: FH - Neurology
    Impact factor: 2.203, year: 2011

    In vivo in rats, galectin-1 had a positive effect on skin wound closure. We describech the differential potential of certain human galectins to induce the conversion of dermal fibroblasts into myofibroblasts and the generation of a bioactive cell culture substratum.
    Permanent Link: http://hdl.handle.net/11104/0202921

     
     
Number of the records: 1  

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