Effect of high phosphorus diet on tooth microstructure of rodent incisors

0368271 - ÚŽFG 2012 RIV US eng J - Journal Article
Jekl, V. - Krejčířová, L. - Buchtová, Marcela - Knotek, Z.
Effect of high phosphorus diet on tooth microstructure of rodent incisors.
Bone. Roč. 49, č. 3 (2011), s. 479-484. ISSN 8756-3282. E-ISSN 1873-2763
Institutional research plan: CEZ:AV0Z50450515
Keywords : Enamel * Hypoplasia * Dentin
Subject RIV: FF - HEENT, Dentistry
Impact factor: 4.023, year: 2011

Enamel hypoplasia and disruption of dentinogenesis are the most common abnormalities of development and mineralization of human teeth. Several reports are available in the literature on the influence of dietary calcium on the formation of human and rodent tooth; however, the information about the influence of dietary phosphorus on the tooth formation is scarce. The aim of the present investigation was to examine the chronic effect of high phosphorus diet and improper dietary calcium to phosphorus ratio on the mandibular incisor microstructure in a hystricomorph rodent - Octodon degu - using macroscopic observation, histopathological examination, transmission and scanning electron microscopy. The present study shows that enamel and dentin development is disturbed under high phosphorus diet and improper calcium to phosphorus ratio. Disturbed mineral metabolism resulted in enamel depigmentation, enamel hypoplasia, enamel pitting and altered dentin morphology.
Permanent Link: http://hdl.handle.net/11104/0202662