Interference of Bifidobacterium choerinum or Escherichia coli Nissle 1917 with Salmonella Typhimurium in gnotobiotic piglets correlates with cytokine patterns in blood and intestine

0367912 - MBÚ 2012 RIV GB eng J - Journal Article
Šplíchalová, Alla - Trebichavský, Ilja - Rada, V. - Vlková, E. - Sonnenborn, U. - Šplíchal, Igor
Interference of Bifidobacterium choerinum or Escherichia coli Nissle 1917 with Salmonella Typhimurium in gnotobiotic piglets correlates with cytokine patterns in blood and intestine.
Clinical and Experimental Immunology. Roč. 163, č. 2 (2011), s. 242-249. ISSN 0009-9104. E-ISSN 1365-2249
R&D Projects: GA ČR GA523/07/0572
Institutional research plan: CEZ:AV0Z50200510
Keywords : Bifidobacterium * gnotobiotic pig * cytokine
Subject RIV: EC - Immunology
Impact factor: 3.360, year: 2011

Gnotobiotic piglets protected by E.coli Nissle 1917 against infection with Salmonella Typhimurium thrived and their wellness correlated with absence of IL-10 in plasma and decrease of TNF-α in plasma and ileum. Piglets associated with Bifidobacterium choerinum and infected with S. Typhimurium suffered by severe systemic infection and mounted similar responses of inflammatory cytokines as piglets infected with S. Typhimurium alone
Permanent Link: http://hdl.handle.net/11104/0202419