Number of the records: 1
Transcriptome alterations in maternal and fetal cells induced by tobacco smoke
- 1.0365848 - ÚEM 2012 RIV GB eng J - Journal Article
Votavová, H. - Dostálová-Merkerová, M. - Fejglová, K. - Vašíková, A. - Krejčík, Z. - Pastorková, Anna - Tabashidze, Nana - Topinka, Jan - Veleminský Jr., M. - Šrám, Radim - Brdička, R.
Transcriptome alterations in maternal and fetal cells induced by tobacco smoke.
Placenta. Roč. 32, č. 10 (2011), s. 763-770. ISSN 0143-4004. E-ISSN 1532-3102
R&D Projects: GA MŠMT 2B06088
Institutional research plan: CEZ:AV0Z50390512
Keywords : maternal smoking * placenta * cord blood
Subject RIV: FP - Other Medical Disciplines
Impact factor: 3.693, year: 2011
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0365848_01.pdf
The study demonstrated that maternal smoking causes significant changes in transcriptome of placental and fetal cells which deregulate numerous biological processes important for growth and development of the fetus. An activation of fetal CYP genes showed a limited ability of the placenta to modulate toxic effects of maternal tobacco use.
Permanent Link: http://hdl.handle.net/11104/0200996
Number of the records: 1