Pro-Oxidant Reactions: Physiological and Pathological Implications

0365380 - FGÚ 2012 RIV IN eng M - Monography Chapter
Rauchová, Hana - Vokurková, Martina - Koudelová, J.
Lipid peroxidation process and some metabolic changes induced by acute hypobaric hypoxia conditions.
Pro-Oxidant Reactions: Physiological and Pathological Implications. Trivandrum: Research Signpost, 2009 - (Díaz-Muňoz, M.; del Angel, A.), s. 105-119. ISBN 978-81-308-0308-1
R&D Projects: GA MŠMT(CZ) 1M0510
Institutional research plan: CEZ:AV0Z50110509
Keywords : brain * thiobarbituric acid-reactive substance * L-carnitine
Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery

Reactive oxygen or nitrogen species have their important roles in cellular signaling pathways, but they are also proposed as mediators of tissue injury in several pathological states, in acceleration of degenerative processes in ageing and in initiation of apoptotic and necrotic processes. In our experiments we used as a model Wistar rats exposed to acute hypobaric hypoxia. The received data seem to be important because variations in oxygen tension represent specific signals capable of regulating the activity of many specific systems in organism
Permanent Link: http://hdl.handle.net/11104/0006593