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Biomedical properties of laser prepared silver-doped hydroxyapatite

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    0365044 - FZÚ 2012 RIV RU eng J - Journal Article
    Jelínek, Miroslav - Weiserová, Marie - Kocourek, Tomáš - Zezulová, Markéta - Strnad, D.
    Biomedical properties of laser prepared silver-doped hydroxyapatite.
    Laser Physics. Roč. 21, č. 7 (2011), 1265-1269. ISSN 1054-660X. E-ISSN 1555-6611
    R&D Projects: GA ČR GA204/07/0325
    Institutional research plan: CEZ:AV0Z10100522; CEZ:AV0Z50200510
    Keywords : silver-doped hydroxyapatite * PLD * layers * antibacterial properties
    Subject RIV: BH - Optics, Masers, Lasers
    Impact factor: 3.605, year: 2011

    Thin films of hydroxyapatite (HA) and silver- doped HA were synthesized using KrF excimer laser deposition. Material was ablated from one target composed from silver and HA segments. Layers properties as silver content, structure, color, FTIR spectra and antibacterial properties (Gram-positive Bacillus subtilis) were measured. Silver concentration in HA layers of 0.06, 0.3, 1.2, 4.4, 8.3, and 13.7 at % was detected. The antibacterial efficacy changed with silver dopation from 71.0 to 99.9%. The focus is on investigation of min- imum Ag concentration needed to reach a high antibacterial efficacy.
    Permanent Link: http://hdl.handle.net/11104/0200382

     
     
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