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Simultaneous analysis of cocaine and its metabolites in urine by capillary electrophoresis - electrospray mass spectrometry using a pressurized liquid junction nanoflow interface

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    0364884 - ÚIACH 2013 RIV DE eng J - Journal Article
    Hezinová, Věra - Aturki, Z. - Klepárník, Karel - D´Orazio, G. - Foret, František - Fanali, S.
    Simultaneous analysis of cocaine and its metabolites in urine by capillary electrophoresis - electrospray mass spectrometry using a pressurized liquid junction nanoflow interface.
    Electrophoresis. Roč. 33, č. 4 (2012), s. 653-660. ISSN 0173-0835. E-ISSN 1522-2683
    R&D Projects: GA ČR GA203/08/1680; GA ČR GAP206/11/2377; GA ČR(CZ) GAP301/11/2055; GA MŠMT LC06023
    Institutional research plan: CEZ:AV0Z40310501
    Keywords : CE-MS * cocaine metabolites * liquid junction interface
    Subject RIV: CB - Analytical Chemistry, Separation
    Impact factor: 3.261, year: 2012

    A new method for the simultaneous separation of cocaine and four metabolites in urine by CE-ESI-MS via a pressurized nano-liquid junction interface was developed. The LODs achieved with the field amplified sample injection method ranged from 1.5 to 10 ng/mL for all the compounds.
    Permanent Link: http://hdl.handle.net/11104/0200253

     
     
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